What is zofran for in pregnancy harmful during
Use of the antiemetic ondansetron during pregnancy was not associated with any adverse for outcomes, an observational study showed. Although the results "cannot definitively rule out the possibility of adverse effects in what is zofran for in pregnancy harmful during with ondansetron, the results do provide reassurance regarding the use of this agent for nausea and vomiting in pregnancy," they wrote in the Feb.
There is not much concern about adverse fetal effects with the drug, but some women are hesitant to use it, according to Loralei Thornburg, MD, of the University of Rochester Medical Center in New York, who specializes in treating high-risk pregnancies.
I took Zofran in pregnancy. My son has a heart defect. I’m not suing. Here’s why.
What the current study "gives women is a confidence that the medications that we're giving them to make them feel better, to help them get through that first trimester feeling better and able to keep things down and function in their daily lives are, in fact, safe for their read more she said what is zofran for in pregnancy harmful during an interview.
Ondansetron is the most common drug used in the U.
Yet despite the widespread use of ondansetron, there are relatively few data on safety for the what is zofran for in pregnancy harmful during.
A prior case-control study showed a significant association between ondansetron and an increased risk of click palate. To explore the safety of the drug, the researchers looked at data from Danish national registries covering January through March The analysis includedpregnancies, of which 0.
Women who had a spontaneous abortion before 6 completed weeks of gestation were excluded. The researchers used propensity scoring to account for the differences between women who took ondansetron during pregnancy and those who did not, pregnancy harmful during 1, to 1, exposed women and 4, to 7, unexposed women what zofran the analyses of the various outcomes.
The mean age of the women in the matched analyses was After adjustment for hospitalization for hyperemesis or pregnancy harmful during and vomiting and for exposure to other antiemetics, ondansetron exposure was not associated with an increased risk of any of the outcomes examined: Spontaneous abortion from 7 to 12 weeks of gestation what is zofran for in pregnancy harmful read article The significantly lower rate of spontaneous abortion in the women exposed to ondansetron should not be interpreted as a protective effect of the drug, according to the researchers.
The findings were consistent what is zofran for in pregnancy harmful during various sensitivity analyses looking at different exposure time windows, birth defects among induced abortions and stillbirths, antihistamine use, and the number of ondansetron prescriptions filled.
Ondansetron Safe for Fetus, Study Affirms
The Best Nursing What is zofran for in pregnancy harmful during of What We Heard This Week. Note that this large retrospective study revealed no association between ondansetron use and adverse fetal outcomes among women in Denmark.
Multiple sensitivity analyses support the primary findings. The study was funded by the Danish Medical Research Council. The pregnancy harmful during reported that they had no conflicts of interest.
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For additional Zofran information, visit our other Zofran pages: If you have been experiencing morning sickness and nausea during your pregnancy, your doctor may have prescribed or spoken to you about taking Zofran.
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While I usually prescribe doxylamine-pyridoxine for morning sickness, some of my patients with severe nausea and vomiting of pregnancy NVP receive ondansetron in hospital. Is ondansetron safe to use during pregnancy? During the past decade ondansetron has been increasingly used in the United States for NVP, owing to the lack of an FDA-approved drug for this condition.
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I never threw up, but you know how your mouth salivates the moment right before before you vomit, that sensation that sends you running to the bathroom? By day four or five I was beside myself. I was drooling on my knees into a trash can or a toilet almost constantly.
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