Rosuvastatin calcium wiki que es
rosuvastatin calcium (CHEBI)
Rosuvastatin INN[3] wiki que under the tradename Crestoris a member of the rosuvastatin calcium class of statinsused in combination with exercise, diet, and weight-loss to treat que cholesterol and related conditions, and to prevent cardiovascular disease. It was developed by Shionogi.
In Crestor was the fourth-highest selling drug in the United States, accounting for approx. The learn more here use of rosuvastatin calcium wiki que es is for the treatment more info dyslipidemia.
The effects of rosuvastatin on LDL cholesterol are dose-related.
Rosuvastatin calcium | C22H28CaFN3O6S+2 - PubChem
Higher wiki que were more efficacious in improving the lipid profile of patients with hypercholesterolemia than milligram-equivalent doses of atorvastatin que milligram-equivalent or higher doses of simvastatin and pravastatin. Meta-analysis showed that rosuvastatin is able to modestly increase levels of HDL cholesterol as rosuvastatin calcium wiki que es, as with other statins.
Que effects are uncommon. The following side effects should be reported to the prescribing doctor if they persist or get worse: The following rare side effects are more serious. Like all statins, rosuvastatin /robaxin-tablets-yeast-infection.html possibly cause myopathyrhabdomyolysis. Stop taking rosuvastatin and contact the prescribing doctor if any of these occur: If any signs of an allergic reaction develop, contact an emergency medical service rosuvastatin calcium wiki Rosuvastatin has multiple contraindicationsconditions that warrant withholding treatment with rosuvastatin, including hypersensitivity to rosuvastatin or any component of the formulation, active liver disease, elevation of serum transaminasespregnancy, or breastfeeding.
The following drugs can have negative interactions with que and should be discussed with rosuvastatin calcium wiki que es prescribing doctor: Rosuvastatin has structural similarities with most other synthetic statinse.
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Rosuvastatin - DrugBank
Crestor wiki que actually rosuvastatin calcium wiki que es calcium salt of rosuvastatin, i. Rosuvastatin is que competitive inhibitor of the enzyme HMG-CoA reductasehaving a mechanism of action rosuvastatin calcium to that of other statins. Putative beneficial effects of rosuvastatin therapy on chronic heart failure may be negated by increases in collagen turnover markers as well as a reduction in plasma coenzyme Q 10 levels in patients with chronic heart failure.
In a Cochrane systematic review the dose-related magnitude of rosuvastatin on blood lipids was determined.
As ofclick at this page had been approved in countries and launched in The results of the JUPITER trial suggested rosuvastatin rosuvastatin calcium wiki que es decrease the relative risk of heart attack and stroke in patients without hyperlipidemiabut with elevated levels of highly sensitive C-reactive protein.
This rosuvastatin calcium strongly impact medical practice by placing many patients on statin prophylaxis who otherwise would rosuvastatin calcium been untreated.
The AURORA trial randomized patients undergoing hemodialysis due to kidney damage to receive either rosuvastatin or placebo. The randomized, double-blind study to found no difference in the two groups in the primary end-point, a combination of cardiovascular mortality, nonfatal myocardial infarction, or nonfatal stroke. The study found no difference wiki que que mortality among this population at a mean follow-up of 3.
Rosuvastatin
According to the FDA, the risk of myopathy during rosuvastatin calcium wiki therapy may be increased in Asian Americans:. Because Asians appear to process the drug differently, half the standard dose can have the same cholesterol-lowering benefit in those patients, though a full dose could increase the risk of side-effects, a study by the drug's manufacturer, AstraZeneca, indicated.
Therefore, physicians should start Asian-American or East Asian patients at que lowest dose level. The main patent protecting rosuvastatin RE37, — due to expire in was challenged as being an improper reissue rosuvastatin calcium an earlier patent.
This challenge was rejected inconfirming protection until In July Mylan gained approval for its generic rosuvastatin calcium. The drug was billed as a "super-statin" during its clinical development; the claim was that it offers high que wiki que improved cholesterol reduction compared to rivals in the class.
The main competitors to rosuvastatin are atorvastatin Lipitor and simvastatin Zocor.
However, people can also combine ezetimibe with either simvastatin or atorvastatin and other agents on their own, for somewhat similar augmented response rates. In Octoberseveral rosuvastatin calcium wiki que es after its introduction in EuropeRichard Hortonthe editor of the medical journal The Lancetcriticized the way Crestor had read article introduced.
The here responded by stating that few drugs had been tested so successfully on so many patients. In correspondence published in The LancetAstraZeneca's CEO Sir Tom McKillop called the editorial "flawed rosuvastatin calcium wiki que es incorrect" and slammed wiki que journal for making "such an outrageous critique of a serious, well-studied medicine.
Registration Confirmation
As with rosuvastatin calcium wiki statins, there is a concern of rhabdomyolysisa severe undesired side effect.
The FDA has indicated that "it does not appear that the risk [of rhabdomyolysis] is greater with Crestor than with other wiki que statins", but has mandated that a warning about this side-effect, as well as a kidney toxicity warning, que added to the product label. From Wikipedia, rosuvastatin calcium wiki que es free encyclopedia.
S4 Prescription only UK: Expert Opinion on Pharmacotherapy.
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Rosuvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. Used as an adjunct to dietary therapy to treat primary hyperlipidemia heterozygous familial and nonfamilial , mixed dyslipidemia and hypertriglyceridemia.
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Rosuvastatin is a prescription medication used to treat high cholesterol levels and to prevent heart disease. Statins help to lower cholesterol levels in the body.
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