The authors sought to compare ondansetron and promethazine among emergency department ED patients phenergan zofran nausea medication phenergan zofran nausea. The hypothesis was that ondansetron was not inferior to promethazine phenergan zofran that rates of adverse effects were similar.
This was a randomized double-blind nausea medication phenergan zofran clinical trial conducted in an urban academic ED. A convenience sample of nonpregnant adults with at least 40 mm of self-reported nausea measured on a mm visual analog scale VAS were enrolled.
Patients who had already received more than 1 L of intravenous fluid or an antiemetic agent nausea medication excluded. Nausea medication phenergan were block-randomized in groups of 10 to either 4 mg of ondansetron zofran 25 mg of promethazine delivered intravenously.
The primary outcome was change in nausea over 30 minutes. The authors used a mm margin of noninferiority.
Secondary endpoints included changes in anxiety, sedation, and other adverse phenergan zofran. Nausea medication phenergan zofran total of subjects completed the study, 60 in each arm. Baseline nausea, anxiety, and sedation scores were similar.
There were no cases of akathisia in the ondansetron group and 2 cases in the nausea medication group. Promethazine and nausea medication phenergan zofran have similar efficacy in reducing nausea among ED patients. Change in nausea medication phenergan zofran was similar, but promethazine was associated with greater sedation.
Phenergan promethazine and Zofran ondansetron. Using promethazine together with ondansetron can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases, conduction abnormalities, or electrolyte disturbances for example, magnesium or potassium loss due to severe or prolonged diarrhea or vomiting.
They both are for nausea or vomiting and can help with some dizziness also. Most people for the record are given Phenergan or promethazine Tablets first and if that does not work they got to the Zofran not only for more effect but the Zofran is much more expensive than the Phenergan.
Everyday Health Drugs Antihistamines Promethazine. What Is Promethazine Phenergan?
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