Msd zocor wiki
Augmentin prescription dosage weightmarketed under the trade name Zocor among others, is a lipid-lowering medication.
Zocor: Uses, Dosage, Side Effects & Warnings -
Serious side effects may include wiki breakdown, liver problems, and increased blood sugar levels. Simvastatin was developed by Merck and came into medical msd zocor wiki in The primary uses of simvastatin are to treat dyslipidemia and to prevent atherosclerosis-related wiki such as stroke and msd zocor wiki attacks in wiki who click here at high risk.
The Heart Protection Study evaluated the effects of simvastatin wiki people with risk factors including existing cardiovascular disease, diabetes, or stroke, but having relatively low LDL cholesterol. Msd zocor this trial, msd zocor lasted 5. Simvastatin has been used to explore whether statins have an effect on delaying on the onset and progression of age-related macular degeneration AMD.
Simvastatin
Msd zocor msd zocor wiki is contraindicated wiki pregnancy, breastfeeding, and liver disease. Patients cannot breastfeed while on simvastatin due to potentially disrupting the infant's lipid metabolism. Rare side effects include joint pain, memory loss, and muscle cramps. A type of DNA variant known as msd zocor single nucleotide polymorphism SNP may msd zocor wiki predict individuals prone to developing myopathy when taking simvastatin; a study ultimately including 32, patients concluded the carriers msd zocor one or two risk alleles of a particular SNP, rs, [16] msd zocor wiki at a five-fold or msd zocor wiki increased risk, respectively.
In Marchthe FDA updated its guidance for statin msd zocor wiki to address reports of memory loss, liver damage, increased blood sugar, development of type 2 diabetesand muscle injury. On March 19,the FDA issued another statement regarding simvastatin, saying it increases the indocin price yahoo answers of muscle injury myopathy when taken at high doses or at lower doses in combination with other drugs.
Simvastatin has important interactions with grapefruit juice and other drugs, including some that are msd zocor wiki used for the treatment of cardiovascular disease. These interactions are wiki important because wiki simvastatin serum levels above those normally provided by the msd zocor wiki recommended dose increases the msd zocor wiki of muscle damage, including the otherwise rare and potentially fatal side effect of rhabdomyolysis.
Consuming large amounts of grapefruit juice increases serum levels of simvastatin by up to three-fold, increasing the risk of side effects. Simvastatin also interacts msd zocor wiki other drugs, including some used msd zocor wiki treat cardiovascular problems.
It should msd zocor wiki be taken by people who are msd zocor wiki taking the antifungal drugs fluconazoleitraconazoleor posaconazole ; the antibiotics msd zocor wiki telithromycin ; HIV protease inhibitors; the antidepressant nefazodone ; the cardiovascular drug gemfibrozil ; the immunosuppressant ciclosporinor the msd zocor wiki drug danazol.
Reduced maximum doses of simvastatin apply for patients taking certain other drugs, including the cardiovascular drugs verapamildiltiazemamiodaroneamlodipineand ranolazine.
Lovastatin
All statins act by inhibiting 3-hydroxymethylglutaryl HMG coenzyme A reductase. Statins are more effective than msd zocor wiki lipid-regulating drugs at lowering LDL -cholesterol concentration, msd zocor wiki they are less effective than the fibrates in reducing triglyceride concentration. However, statins reduce cardiovascular disease events and total mortality irrespective of the initial cholesterol concentration.
This is a major piece of evidence that statins work in another way msd zocor wiki the lowering of cholesterol called pleiotropic effects. The drug is in the form of an inactive lactone that is hydrolyzed after ingestion to produce the msd zocor wiki agent.
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Medically reviewed on Nov 9, Zocor is used to lower cholesterol and triglycerides types of fat in the blood. It is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors.
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Lovastatin Merck's Mevacor is a statin drug, used for lowering cholesterol in those with hypercholesterolemia to reduce risk of cardiovascular disease. Lovastatin is a naturally occurring compound found in low concentrations in food such as oyster mushrooms , [2] red yeast rice , [3] and Pu-erh. The primary uses of lovastatin is for the treatment of dyslipidemia and the prevention of cardiovascular disease.
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It is a combination of ezetimibe known as Zetia in the United States and Ezetrol elsewhere and the statin drug simvastatin known as Zocor in the U. Ezetimibe reduces blood cholesterol by acting at the brush border of the small intestine and inhibiting the absorption of cholesterol, leading to a decrease in the delivery of intestinal cholesterol to the liver.
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