Lithium fact sheet 2017

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Medically reviewed on Oct 1, Lithium toxicity is closely sheet 2017 to serum lithium concentrations, and can occur at doses close to therapeutic concentrations.

Lithium Carbonate - FDA prescribing information, side effects and uses

Facilities for prompt and accurate serum lithium determinations should be available before initiating treatment [see Dosage and Administration 2. Lithium is a mood-stabilizing agent indicated for the treatment of manic episodes and as maintenance treatment for Bipolar I Disorder.

lithium fact sheet 2017

Before initiating treatment with lithium, renal function, vital signs, serum electrolytes, /overdose-on-wellbutrin-amount.html thyroid function should be evaluated. Concurrent medications should be assessed, and if the patient is a woman of childbearing potential, pregnancy status and potential should be considered.

Consider medical conditions and drug interactions sheet 2017 would affect lithium lithium fact sheet 2017 and administration [see Warnings and Precautions 5. In the absence of medical conditions and concomitant medications that would suggest starting at a lower dose, the recommended starting dose in adults is:.

Obtain serum lithium concentration assay after 4 days, drawn 12 hours after the last oral dose. Adjust daily dosage based on serum lithium concentration and clinical response. Fine hand tremor, polyuria lithium fact sheet 2017 mild thirst may occur during initial therapy for the acute manic phase, and may persist throughout treatment. Transient and mild nausea and general discomfort may also appear during the first few days of lithium administration.

These here reactions may subside with continued treatment, lithium fact sheet 2017 administration with food, temporary reduction or cessation of dosage.

Lithium Carbonate

Titrate to serum lithium concentrations between 0. Obtain serum lithium concentrations regularly until the serum concentration and clinical condition of the lithium fact sheet 2017 has stabilized [see Dosage and Administration 2.

Dosage recommendations for lithium in patients 12 years and older are sheet 2017 to that of adults [see Specific Populations 8. Blood samples for serum lithium determination should be drawn immediately prior to the next dose lithium fact sheet 2017 lithium concentrations are relatively stable i.

Total reliance must not sheet 2017 placed on serum concentrations alone. Click to see more patient evaluation requires both sheet 2017 and laboratory analysis.

In addition to lithium fact sheet 2017 monitoring of serum lithium concentrations for patients on sheet 2017 treatment, serum lithium concentrations should be sheet lithium fact after any change in dosage, concurrent medication e. Patients abnormally sensitive to lithium may exhibit toxic signs at serum concentrations that are within lithium fact is considered the therapeutic range.

Geriatric patients often respond to reduced dosage, and may exhibit signs of toxicity at serum concentrations lithium fact sheet 2017 tolerated by other patients [see Specific Populations 8. If the decision is made to continue lithium treatment during pregnancy, monitor serum lithium concentrations and adjust the dosage as needed in a pregnant woman because renal lithium clearance increases during pregnancy.

Avoid sheet 2017 restriction or diuretic sheet 2017. To decrease the sheet 2017 of postpartum here intoxication, decrease or discontinue lithium therapy two to three days before the expected delivery date to reduce neonatal concentrations and reduce sheet 2017 risk of maternal lithium intoxication due to the change in lithium fact volume which occurs during delivery. At delivery, vascular volume sheet 2017 decreases and the renal clearance of lithium may decrease to pre-pregnancy concentrations.

Restart treatment at the preconception dose when the patient is medically rosuvastatin calcium 10mg vs crestor after delivery with careful monitoring of serum lithium concentrations [see Warnings and Precautions 5. Titrate slowly while frequently monitoring serum lithium concentrations lithium fact sheet 2017 monitoring for signs of lithium fact sheet 2017 toxicity.

Each mg capsule for oral administration contains: Lithium is contraindicated in patients with known hypersensitivity to any lithium fact ingredient in the Lithium Carbonate capsule [see Adverse Reactions 6Description sheet 2017 ]. Some patients abnormally sensitive to lithium may exhibit toxic signs at serum concentrations that are considered within the therapeutic range [see Boxed Warning, Dosage and Administration 2.

Lithium may take lithium fact sheet to 24 hours to distribute into brain tissue, so occurrence lithium fact sheet 2017 acute toxicity symptoms may be delayed.

At higher concentrations, giddiness, ataxia, blurred vision, tinnitus and a large output of dilute urine may be seen. Neurological signs of lithium toxicity range from mild neurological adverse reactions such as fine 2017, lightheadedness, and weakness; sheet 2017 moderate manifestations like apathy, drowsiness, hyperreflexia, muscle twitching, and slurred speech; and severe manifestations such sheet 2017 clonus, confusion, seizure, coma is zoloft good cause weight gain death.

Cardiac manifestations involve electrocardiographic read article, such as prolonged QT interval, ST and T-wave changes sheet 2017 myocarditis.

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