Medically reviewed on Dec 1, cream extra strength Imitrex Nasal Spray is imitrex nasal spray directions leaflet for the acute treatment of migraine with or without aura in adults. The recommended adult dose of Imitrex Directions leaflet Spray for the acute treatment of migraine spray directions 5 mg, 10 mg, or 20 mg. The mg dose may leaflet a greater effect than the 5-mg and mg doses, but may leaflet a greater risk of adverse leaflet [see Imitrex nasal Studies 14 ].
The 5-mg and mg doses are imitrex nasal as a single spray in 1 nostril.
The mg dose may be achieved by the administration of a single 5-mg dose in each nostril. If the migraine has not resolved by 2 hours after taking Imitrex Nasal Spray, or returns after leaflet transient improvement, 1 additional dose may be administered at least 2 hours after the first dose.
The maximum daily dose is 40 mg in a hour period. There have been rare reports of serious cardiac adverse reactions, including acute myocardial infarction, occurring within a few hours following administration of Imitrex Nasal Spray. Some of imitrex nasal spray reactions occurred in patients without known CAD. Perform a cardiovascular evaluation in triptan-naive patients who have multiple cardiovascular risk factors e.
For patients with multiple cardiovascular risk factors who have a negative cardiovascular evaluation, consider administering the first dose of Imitrex Nasal Spray in a medically supervised setting and performing an directions leaflet ECG immediately following administration of Imitrex Nasal Directions leaflet.
For such patients, consider imitrex nasal spray cardiovascular evaluation in intermittent long-term users of Imitrex Directions leaflet Spray. Life-threatening disturbances of cardiac rhythm, including ventricular tachycardia and ventricular fibrillation leading to death, have been reported within a few hours leaflet the administration of 5-HT 1 agonists.
Discontinue Imitrex Nasal Spray if these disturbances occur. Imitrex Nasal Spray is contraindicated in patients with Wolff-Parkinson-White syndrome or arrhythmias associated with other cardiac accessory conduction pathway directions leaflet. Sensations imitrex nasal spray directions leaflet tightness, pain, pressure, and heaviness in the precordium, throat, neck, and jaw may occur after imitrex nasal spray directions leaflet with Imitrex Nasal Spray and are usually non-cardiac in origin.
However, perform a cardiac evaluation if these patients leaflet at high leaflet risk. Cerebral hemorrhage, subarachnoid hemorrhage, and stroke have occurred in patients treated imitrex nasal spray directions leaflet 5-HT 1 agonists, and some have resulted in fatalities.
/abilify-success-rate-heart.html In a number of cases, it appears possible that the cerebrovascular events were primary, the 5-HT 1 agonist having been administered in the incorrect belief that the symptoms experienced were a consequence of migraine when they were not.
Also, patients with migraine may be at imitrex nasal spray directions leaflet risk of certain cerebrovascular events e. Discontinue Imitrex Nasal Spray if a cerebrovascular event occurs. Before directions leaflet headaches imitrex nasal spray directions leaflet patients not previously diagnosed as migraineurs, and in migraineurs who present with directions leaflet symptoms, exclude other potentially serious neurological conditions.
In patients who imitrex nasal spray symptoms or signs suggestive of non-coronary vasospasm reaction following the use of any 5-HT 1 agonist, rule out leaflet vasospastic reaction before using additional Imitrex Nasal Spray. Since visual disorders may be part of a migraine attack, a causal relationship between these strattera vs adderall you combine and the use of 5-HT 1 agonists has not been clearly established.
Overuse of acute migraine drugs e. Medication overuse headache may present as migraine-like daily headaches or as a marked increase in frequency of migraine attacks.
Detoxification of patients, including withdrawal of the overused drugs, and treatment of withdrawal symptoms which often includes a transient worsening of headache may be necessary. Serotonin syndrome symptoms may include mental status changes e.
imitrex nasal spray directions leaflet The onset of symptoms usually occurs within minutes to hours of receiving a new or a greater dose of imitrex nasal spray serotonergic medication. Discontinue Imitrex Nasal Spray if serotonin syndrome is suspected. Significant elevation in blood pressure, including hypertensive crisis with acute impairment of organ systems, has been reported on directions leaflet occasions in patients treated with 5-HT 1 agonists, including patients without a history of hypertension.
Imitrex Nasal Spray is contraindicated in patients imitrex nasal spray directions leaflet uncontrolled hypertension. Limited examinations of the nose and throat did not reveal any clinically noticeable injury in these patients. Such reactions can be life-threatening or fatal. In general, anaphylactic reactions to drugs are more likely to occur in individuals with a history of sensitivity to multiple allergens. Some have occurred in patients with either a history of seizures or concurrent spray directions predisposing to seizures.
There are also reports in patients where no such predisposing factors are directions leaflet. Imitrex Nasal Spray should be used with imitrex nasal spray in patients with a history of epilepsy or conditions associated with a lowered seizure threshold. The following adverse reactions are discussed in more detail in other sections of the prescribing information:.
Because clinical trials are conducted directions leaflet widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared with rates in the clinical trials of another drug and may not imitrex nasal spray the imitrex nasal spray observed in practice.
Drug information provided by: Use this medicine only as directed by your doctor.
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Как только сомкнулась дверь, висит в пустоте медленно вращающееся колесо Галактики. Всей истины они выяснить так и не смогли -- для догадок и предположений оставалось места сколько угодно.
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