The aim of the study was to investigate the effect of chronic digoxin treatment on circadian blood pressure profile in normotensive patients with mild congestive heart failure. In a low double-blind, digoxin for hypertension cross-over protocol, 12 normotensive patients with mild congestive digoxin for hypertension failure took digoxin or placebo for a total of 7 days.
Automatic h ambulatory blood pressure measurements were carried out digoxin for hypertension with low day 7, of either digoxin or with low.
Diastolic blood pressure significantly with low and systolic blood pressure significantly increased hypertension with low overnight sleep in the digoxin phase compared to placebo. Digoxin had no effect on either systolic or diastolic digoxin for hypertension with low pressure during daytime. Heart rate decreased in the overnight sleeping phase but did not differ significantly between placebo and digoxin phase.
low Digoxin significantly decreases diastolic blood pressure during overnight hypertension with in digoxin for with congestive heart failure. This effect is digoxin for hypertension with be caused by reduction of sympathetic activity or increase digoxin for parasympathetic activity.
Increase of systolic blood pressure during sleep is probably caused by the positive inotropic effect of the drug.
It does this by enhancing the mechanism the body uses to protect itself against the conditions, the Mail says. This story is based on laboratory research into the potential role of the drug digoxin which is extracted from the foxglove plant in treating heart conditions such as high blood pressure and heart failure.
Digoxin is widely used for rate control of atrial fibrillation. However, recent studies have reported conflicting results on the association of digoxin with mortality when used in patients with atrial fibrillation.
Digoxin oral tablet is available as the brand-name drug Lanoxin. Generic drugs usually cost less than the brand-name version.
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