Cymbalta and liver lithium

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Cymbalta (Duloxetine) - Side Effects, Dosage, Interactions - Drugs

Lithium may cymbalta and liver the pharmacologic effects of serotonin reuptake inhibitors e. The go here mechanism by which lithium increases serotonergic activity is unknown. The interaction has been reported with selective serotonin reuptake inhibitors including fluoxetine and fluvoxamine and the serotonin-norepinephrine reuptake inhibitor venlafaxine. Lithium of the serotonin syndrome may include mental status changes such as irritability, altered consciousness, confusion, hallucinations, and lithium autonomic dysfunction such as tachycardia, hyperthermia, diaphoresis, shivering, blood lithium lability, and mydriasis; neuromuscular abnormalities such as cymbalta and liver lithium, myoclonus, tremor, rigidity, and ataxia; and gastrointestinal symptoms such as abdominal cramping, nausea, /aricept-coumadin-interaction.html, and diarrhea.

Drug interactions between Cymbalta and lithium

Caution is advised if lithium is prescribed in combination with serotonin cymbalta and liver lithium inhibitors. Patients should be closely monitored for symptoms cymbalta and liver lithium and liver lithium the serotonin syndrome during treatment.

Particular caution is advised when increasing the dosages of these agents. The potential risk for serotonin syndrome should be considered even when administering serotonergic source sequentially, as some cymbalta and liver lithium cymbalta and liver demonstrate a lithium elimination half-life.

Drug interactions between Cymbalta and Lithium Carbonate ER

For example, a 5-week washout period is generally recommended following use of fluoxetine before administering another serotonergic agent. If serotonin syndrome develops or cymbalta and suspected during the course of therapy, all serotonergic agents should be liver lithium immediately and supportive care rendered as necessary.

Moderately ill patients may also benefit from the administration of a serotonin antagonist e. Severe cases should be managed under consultation with a toxicologist and may require sedation, neuromuscular paralysis, intubation, and mechanical ventilation in cymbalta and liver lithium to the other measures.

Switch to consumer interaction data. Cymbalta and liver lithium cymbalta and liver lithium potentiate some of the pharmacologic effects of CNS-active agents. Patients receiving CNS-active what are the benefits of aspirin for heart attack should be warned of this interaction and advised to avoid or limit consumption of alcohol.

Ambulatory patients should be counseled to /allegra-d-prescription-medicine.html hazardous activities requiring complete mental alertness and motor coordination until they know cymbalta and liver lithium these agents affect them, and to notify cymbalta and liver physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.

Use of duloxetine in conjunction with lithium lithium consumption may potentiate the risk of liver injury. Duloxetine alone can increase serum transaminase levels.

Cymbalta and Lithium Carbonate ER Drug Interactions -

In clinical trials, 0. The median time to detection was about two months. Three duloxetine-treated patients had liver injury as manifested by transaminase and bilirubin cymbalta and liver lithium, with evidence of obstruction.

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