Compazine half life half life

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Use with caution in this age group in psychotic disorders. Owing to the susceptibility of compazine half life half life patients to centrally acting drugs, lower initial dosage more info recommended. Care should be taken not to confuse adverse effects of prochlorperazine eg orthostatic hypotension with effects due to the primary disorder.

Prochlorperazine Tablets BP 5mg

After several weeks of compazine half life half life, dosage may be gradually reduced to mg daily. Schizophrenia and other psychotic disorders: Usually mg daily, but patients vary widely in response. The following dosage regime is /normal-tegretol-level-high.html After some weeks at the effective dosage level, an attempt should be made to reduce the dosage.

Total daily dosages as low as 50mg, or even 25mg, have sometimes found compazine half life half life be adequate.

Prochlorperazine

It should be avoided in patients known compazine half life half life be hypersensitive to phenothiazine or with a history of narrow see more glaucoma or agranulocytosis. The occurrence of unexplained infections or fever may be evidence of blood dyscrasia see section 4. Signs of autonomic dysfunction, such as compazine half life half life compazine half life half life arterial instability, may precede the onset of hyperthermia and serve as early warning signs.

Although neuroleptic malignant syndrome may be idiosyncratic in origin, dehydration and organic brain disease are predisposing factors. Compazine half life half life with caution in the elderly, especially during compazine half life half life hot or very cold weather due to the risk of hyper- hypothermia.

Prochlorperazine should be used cautiously in the elderly owing to their susceptibility to drugs acting centrally on the nervous system. There is an increased risk of drug-induced parkinsonism in the elderly particularly after compazine half life half life compazine half life half life.

Care should also be taken not to confuse the adverse effects of prochlorperazine, e.

Prochlorperazine Tablets BP 5mg - Summary of Product Characteristics (SmPC) - (eMC)

As with other neuroleptics, cases of QT interval prolongation have been reported with prochlorperazine very rarely see section 4.

The risk-benefit should be fully assessed before prochlorperazine treatment is commenced, and patients with predisposing factors for ventricular arrhythmias, e. Recurrence of psychotic symptoms may also occur, and the compazine half life half life of involuntary movement disorders such as akathisia, dystonia and dyskinesia has been reported.

Therefore, gradual withdrawal is advisable. Since patients treated with antipsychotics often present with acquired risk factors for VTE, all possible risk factors for VTE should be identified before and during treatment with prochloperazine and preventative compazine half life half life undertaken.

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