There is no evidence that the use of antiviral agents in women who are pregnant and have a history of genital herpes prevents perinatal transmission of herpes simplex virus HSV to neonates. A, based on multiple systematic reviews].
However, treatment with antivirals during the last month of pregnancy does reduce the rate of HSV outbreaks in pregnant women and the resultant need for cesarean delivery.
Neonatal herpes infection is the major consequence of maternal Click to see more. Fortunately, the transmission rate is quite low less than 1 percent for nonprimary HSV can you use zovirax during pregnancy quiz. This poses a problem in assessing the effectiveness of antivirals for preventing this serious illness, because even a large meta-analysis is underpowered in addressing this issue.
One systematic review and one meta-analysis reviewed a total of five randomized controlled trials. Both reviews were of good quality. The trials involved pregnant women with recurrent and first-episode HSV infections. The dosages of acyclovir ranged from to 1, mg per day.
Acyclovir was the only antiviral agent evaluated in either study. The aggregate data involved nearly patients. There were no reported cases of neonatal HSV infection in either the treatment or placebo groups. The National Guideline for the Management of Genital Herpes, published by the Association for Genitourinary Medicine and the Medical Society for the Study of Venereal Disease, recommends the use of continuous acyclovir during the last month of pregnancy as a treatment option in women with recurrent can you use can you use during pregnancy quiz herpes.
ACOG also can you use zovirax during pregnancy quiz that for zovirax during at pregnancy quiz of recurrent HSV, initiation of antiviral therapy more info the last month of pregnancy may be warranted.
With the evidence that antiviral use zovirax reduces the can you use of maternal HSV outbreaks in the perinatal can you and subsequent cesarean deliveries, one can you use zovirax during pregnancy quiz argue that zovirax during pregnancy you use zovirax during pregnancy quiz morbidity and costs are decreased with treatment.
Quiz cheap, safe medicine acyclovir and a small NNT of 93 add credence to this argument. Despite the lack of data regarding the outcome of neonatal HSV infection, the sample size required is so large that such a study may never be performed. Thus, acyclovir use for the prevention of during pregnancy HSV in the final month of pregnancy appears to be a reasonable treatment option.
Already a member or subscriber? Address correspondence by e-mail to Christopher Wenner, M. Reprints are not available from the authors. Centers for Disease Control and Prevention.
Sexually transmitted diseases treatment guidelines Accessed online August 19,at: Acyclovir prophylaxis to prevent herpes simplex virus recurrence /nizoral-shampoo-instructions-singapore.html delivery: Management of herpes in pregnancy. Number 8, October Clinical management guidelines for obstetrician-gynecologists.
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