Amantadine for ms side effects

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Amantadine for fatigue in multiple sclerosis.

Fatigue is one of the most common amantadine for ms side effects disabling symptoms of people with Multiple Sclerosis MS. The effective management of fatigue has an important impact on the patient's functioning, abilities, and quality of life.

Although a number of strategies have been devised for reducing fatigue, treatment recommendations are based on amantadine for ms side effects limited amount of amantadine for evidence. Many textbooks report amantadine as a first-choice drug for MS-related fatigue side effects of published randomised controlled trials RCTs showing some benefit. Amantadine for ms side effects performed a systematic review in order to gather existing evidence, and contribute to the topic.

The effect of amantadine for the treatment of fatigue in people with multiple sclerosis

To determine the effectiveness and safety of amantadine in reducing fatigue in people with MS. Randomised, placebo or other drugs-controlled, double-blind trials of /feldene-gel-what-is-it-used-for-25g.html in MS people with fatigue. Three reviewers selected studies for inclusion in the review and amantadine for ms side effects extracted the data reported amantadine for ms side effects the original articles.

Missing and unclear data were requested by correspondence side effects the trial's principal investigator. A meta-analysis was not performed due to the inadequacy of available data, heterogeneity of outcome measures.

Amantadine

Out of twelve pertinent side amantadine for, four trials met the criteria for inclusion in this review: The number of randomised participants ranged between 10 andand a total of MS patients side effects been studied. Overall the quality of the studies side effects /effexor-xr-225-mg-reviews-link.html poor and all trials were open to bias.

All studies reported small and inconstant improvements in fatigue, whereas the clinical relevance of these findings and the impact on patient's functioning and health related quality of life remains undetermined. Amantadine treatment is overall amantadine for ms side effects tolerated, however its efficacy in reducing fatigue in people with MS is poorly documented and there is insufficient evidence to make recommendations to guide prescribing.

It is advisable to a improve knowledge on the underlying mechanisms of MS-related fatigue; b achieve an agreement on accurate, reliable and responsive outcome measures of fatigue; c perform good quality RCTs.

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